The reason this has come up recently is because of my work computer. It has a wired mouse and although I have been using this computer for about a year now, the chord still gets in the way. It tends to bump into the monitor stand. This is not a big problem, just a minor annoyance. At home I only have one monitor so my mouse chord never interferes with the stand.
I wish I could get feedback from folks who have used both to find out what their preference is and if there are any pitfalls with the wireless device that I don't know about. Oh right, I should be using Twitter for that, not my blog with a readership of 4 non-technical peoples. My bad :)